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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14881 | CB1 antagonist 2 | AM4113 | Cannabinoid Receptor |
CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM. | |||
T41350 | 6-Bromopravadoline | WIN 54461 | Cannabinoid Receptor |
6-Bromopravadoline (WIN 54461) (WIN 54461) is an antagonist of CB1. 6-Bromopravadoline acts as an inhibitor of the binding of [3H]Win 55212-2 (IC 50 =515 nM) reflective of cannabinoid receptor binding [1] [2]. | |||
TN1465 | Cannabigerol | NOS , 5-HT Receptor , ROS | |
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur... | |||
T8511 | TM38837 | Cannabinoid Receptor | |
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes. | |||
TN5131 | Tetrahydrocannabivarin | THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin | Cannabinoid Receptor |
Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in ob... | |||
T68515 | AZD-1175 | ||
AZD-1175 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes and obesity. | |||
T68500 | AZD-2207 | ||
AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes mellitus and obesity. | |||
T21914 | (S)-SLV 319 | ||
Ibipinabant (SLV319) is a potent, selective, and orally active antagonist of the cannabinoid CB1 receptor, demonstrating a K i of 7.8 nM and exhibiting over 1000-fold selectivity for CB1 compared to CB2 (K i =7943 nM). I... | |||
T78674 | Isopropyl dodec-11-enylfluorophosphonate | IDEFP | FAAH |
Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits equipotent inhibition of fatty acid amide hydrolase (FAAH), with b... | |||
T38199 | (±)-WIN 55,212 (mesylate) | ||
(±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively.... | |||
T23099 | O-2050 | Others | |
O-2050 is a high affinity cannabinoid CB 1 receptor antagonist with a K i of 2.5 nM. O-2050 inhibits cannabinoid CB 2 receptor with Ki of 0.2 nM. O-2050 decreased food intake in mice and caused locomotor stimulation in m... | |||
T35468 | (±)19(20)-EDP Ethanolamide | ||
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). It is produced through direct epoxygenation of docosahexaenoyl et... |